From antibodies against viruses, to lipid transporters for the outer membranes of bacteria and organelles

 

We have investigated the structure and function of a wide-range of proteins involved in infection and host-immunity, as well as some collaborative efforts in enzymology and protein design.  As a part of the Skirball Institute of Biomolecular Medicine, we have access to state of the art robotics for nanoliter crystallization and automated plate imaging, and are just a short drive from the National Synchrotron Light Source II--the newest and brightest synchrotron X-ray source in the United States.  And through a major new initiative, the Skirball Institute will be purchasing three brand-new electron microscopes for structural biology: a Titan Krios and a Talos Arctica for high-resolution cryo EM, and a Talos 120, for cryo screening and negative-stain EM studies.